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Dapoxetine: Drug for Premature Ejaculation

 

A new drug application for dapoxetine is currently under review by the U.S. Food and Drug Administration (FDA), and if approved, it will be the first prescription product indicated for the treatment of ...

 

Distribution Source : BuyviagraX.com
Date : July 25, 2016

 

A new drug application for dapoxetine is currently under review by the U.S. Food and Drug Administration (FDA), and if approved, it will be the first prescription product indicated for the treatment of Premature Ejaculation. As said by Dr. Jon Pryor, professor and chairman of the department of urological surgery at the University of Minnesota's Cities campus in Minneapolis "Premature Ejaculation is the most common male sexual dysfunction and about 20 percent of adult males have premature ejaculation at any one time, and 70 percent of men experience premature ejaculation at some time during their lives."

 

This new drug is meant to treat premature ejaculation and it's estimated that it could make a bigger impact on the male sexual health market than Pfizer's impotence blockbuster Viagra.

 

As compared to erectile dysfunction it has been estimated that PE may effect 27% to 34% of man across all age ranges, while ED is estimated to affect 10% to 12% of all men, who are usually older than age. Although PE is common it still remains widely under-diagnosed and under-treated.

 

As soon as dapoxetine receives FDA approval, the potential market for it is huge, though doctors said that it depends on other factors. "Mainly a lot will depend on how aggressively the company will use direct to consumer advertising for PE" said Dr. Jonathan Jarow, Professor of Urology. He said that other drugs in the same class as dapoxetine are now prescribed by doctors for premature ejaculation and are recognized by the American Urological Association as treatments of the condition, but prescriptions of these medications- called selective serotonin- are for off label use and cannot be advertised.

 

Researchers took 2614 men with PE and followed them for 12 weeks. The men were instructed to take a pill 1 to 3 hours before they planned to have sex. Though they didn't know it, some of the men were taking dapoxetine while others were taking a dummy pill, or placebo. Their partners-women--held a stopwatch to time the period between penetration and orgasm. The men taking the placebo increased their time to ejaculation from about one minute to just less than two minutes, on average. The real drug, however, had a bigger effect. Men who took 30 mg. of dapoxetine held off their orgasm for nearly three minutes. Men on a 60 mg. dose did so for about three and a half minutes. A lot more men taking the drug rated their feelings of satisfaction as good or very good." The big increase was in sexual satisfaction rather being focused on time and only time."

 

The percentage of men rating control over ejaculation as "fair to very good" increased dramatically for dapoxetine 30 mg (2.5% to 51.8%) and 60 mg (3.3% to 58.4%) compared to placebo (3.5% to 26.4%).

 

The percentage of men rating sexual satisfaction as "good to very good" almost doubled with dapoxetine 30 mg (20.2% to 38.7%) and 60 mg (22.3% to 46.5%), respectively, in comparison to placebo (21.6% to 24.6%).

 

The percentage of partners rating sexual satisfaction as "good to very good" almost doubled with dapoxetine 30 mg (20.4% to 39%) and 60 mg (24.8% to 47.4%), respectively, compared to placebo (20.1% to 25.2%).

 

Dapoxetine can be taken as needed, just a few hours before a person plans to have sex, so it is relatively convenient. Other drugs-antidepressants-used to treat PE need to be taken continuously. Now one can comfortably get the pill from a general physician rather that going to a sex therapist.

 

But there are some cautions as the drug isn't approved yet it is still waiting for FDA approval. The drug has side effects: 20 percent of men taking the higher dosage reported feeling nauseous. And many psychologists believe that the drug alone is not enough, it will work best paired with therapy to deal with feelings of inadequacy or anxiety that may contribute to PE.

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